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. Author manuscript; available in PMC: 2021 May 18.
Published in final edited form as: J Neural Eng. 2015 Oct 19;12(6):066018. doi: 10.1088/1741-2560/12/6/066018

Table 1.

Number of tissue samples near identified electrode tips that received each score given by the histopathologist, who had been blinded to the stimulation condition. The only group whose score distribution was significantly different from the control condition was the 20 μA, 1/3 duty cycle, 5 s condition (p = 0.03, Fisher–Freeman–Halton exact test).

Amp. (μA) 10 20 20 20 20 100 100
Duty cycle Control 1/1 1/3 1/3 1/1 1/1 1/3 1/1
Duration (s) 5 1 5 1 5 1 1

No damage 25 3 11 6 1 6 3 4
Scarring Minimal 11 1 4 8 0 1 1 0
Mild   0 0 0 0 0 0 0 0

No damage 15 0 6 4 1 5 1 4
Gliosis Minimal 18 3 9 4 0 2 3 0
Mild   3 1 0 6 0 0 0 0