Table 2.
Predictors of post-COVID syndrome (PCS) based on an uni- and multivariable logistic regression model.
Post-COVID-19 syndrome |
Univariate regression |
Multivariable regression |
|||||
---|---|---|---|---|---|---|---|
No (n = 230) | Yes (n = 123) | OR (95% CI)* | p-value | aOR (95% CI)* | p-value | ||
Male | 112 (48•7%) | 39 (31•7%) | 0•49 (0•31–0•77) | •002 | 0•59 (0•36–0•98) | •040 | |
Female | 118 (51•3%) | 84 (68•3%) | ref• | ||||
Median Age (IQR) | 49 (35–56) | 47 (33–56) | 0•99 (0•97–1•01) | •435 | |||
Preconditions | 63 (28•8%) | 31 (26•3%) | 0•88 (0•53–1•46) | •626 | |||
Hospitalisation | 8 (3•6%) | 0 | n•a• | ||||
Symptoms during acute phase | Median duration (days; IQR) | 13 (8–16) | 14 (11–21) | 1•04 (0•91–1•07) | •201 | ||
Number of symptoms (median; IQR) | 4 (2–5) | 5 (3–6) | 1•28 (1•13–1•46) | <0•001 | 1•29 (1•08–1•55) | •005 | |
Fever | 104 (45•2%) | 48 (39•0%) | 0•78 (0•50–1•21) | •263 | |||
Cough | 147 (63•9%) | 87 (70•7%) | 1•37 (0•85–2•19) | •179 | 0•94 (0•53–1•67) | •824 | |
Sore Throat | 72 (31•2%) | 45 (36•6%) | 1•27 (0•81–2•00) | •316 | |||
Rhinitis | 75 (32•6%) | 44 (35•8%) | 1•15 (0•73–1•82) | •549 | |||
Muscle and/or body aches | 122 (53•0%) | 71 (57•7%) | 1•21 (0•78–1•88) | •400 | |||
Headache | 112 (48•7%) | 71 (57•7%) | 1•44 (0•93–2•23) | •106 | 0•84 (0•48–1•47) | •537 | |
Diarrhoea | 25 (10•9%) | 26 (21•1%) | 2•19 (1•21–4•00) | •010 | 1•50 (0•78–2•91) | •277 | |
Anosmia | 117 (57•0%) | 85 (42•1%) | |||||
Ageusia | 94 (51•4%) | 89 (48•6%) | |||||
IgG Level | IgG categories | ||||||
IgG ≤ 1•1 | 28 (12•8) | 21 (17•6) | 1•92 (0•99–3•72) | •054 | 2•05 (0•99–4•22) | •051 | |
IgG 1•2 - 4 | 76 (34•7) | 53 (44•5) | 1•78 (1•09–2•91) | •021 | 1•90 (1•13–3•18) | •015 | |
IgG > 4 | 115 (52•5) | 45 (37•8) | ref• | ref• | |||
1st Visit (S/CO-Ratio, median IQR) | 4 (2–7) | 3 (1–6) | |||||
2nd Visit (S/CO-Ratio, median IQR) | 3 (2–5) | 2 (1–4) | |||||
3rd Visit (S/CO-Ratio, median IQR) | 2 (1–4) | 2 (1–4) |
Odds-Ratio, 95% confidence interval and p-value obtained using binary logistic regression. n, number; OR, Odds-Ratio; aOR, adjusted Odds-Ratio; ref, reference; n/a, not applicable, IQR, interquartile range; S/CO-Ratio, signal-to-cutoff Ratio.