Table A12:
Adverse Events | Facial Muscle Twitching | Agitationa | Worsening Mood, Anxiety, Depressionb | Difficulty Concentratingc | Impaired Cognition | Impaired Memory | Falls | Lactation | Tremor | Aversive Tactile Artifact | Unpleasant Feelings | Suicidal Thoughts |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Blumberger et al, 201682 | Bi 0/40 Uni 1/40 Sham 0/41 | Bi 3/40 Uni 3/40 Sham 1/41 | Bi 1/40 Uni 0/40 Sham 0/41 | Bi 0/40 Uni 0/40 Sham 1/41 | Bi 0/40 Uni 0/40 Sham 1/41 | |||||||
Boutros et al, 2002186 | rTMS 5/12 Sham 0/9 | |||||||||||
Brunelin et al, 2014116d | rTMS 5/104 Sham 7/51 | |||||||||||
George et al, 201089 | rTMS 0/92 Sham 1/98 | rTMS 6/92 Sham 8/98 | ||||||||||
Kaster et al, 201848 | rTMS 0/25 Sham 1/27 | |||||||||||
Levkovitz et al, 2015126 | rTMS 0/89 Sham 2/92 | |||||||||||
Loo et al, 2003120 | rTMS 3/9 Sham 0/10 | |||||||||||
Loo et al, 200793 | rTMS 3/18 Sham 0/18 | rTMS 1/18 Sham 0/18 | rTMS 1/18 Sham 0/18 | |||||||||
Mantovani et al, 2013104 | rTMS 1/12 Sham 2/13 | rTMS 1/12 Sham 1/13 | rTMS 1/12 Sham 1/13 | |||||||||
Mosimann et al, 200494 | rTMS 1/15 Sham 0/9 | |||||||||||
O'Reardon et al, 200795 | rTMS 34/165 Sham 5/158 | |||||||||||
Padberg et al, 2002111e | 100% 2/10 90% 3/10 Sham 0/10 | 100% 2/10 90% 3/10 Sham 0/10 | ||||||||||
Plewnia et al, 2014125 | rTMS 1/16 Sham 0/16 | |||||||||||
Tavares et al, 2017110 | rTMS 6/20 Sham 5/23 | |||||||||||
Triggs et al, 201076 | rTMS 1/18 Sham 0/7 | |||||||||||
Yesavage et al, 201850 | rTMS 8/73 Sham 3/77 | rTMS 3/73 Sham 7/77 | rTMS 3/73 Sham 4/77 | |||||||||
Total | rTMS 38/293 Sham 6/281 | rTMS 2/98 Sham 0/59 | rTMS 29/490 Sham 22/414 | rTMS 12/44 Sham 7/45 | rTMS 1/12 Sham 1/13 | rTMS 1/12 Sham 1/13 | rTMS 3/73 Sham 7/77 | rTMS 1/80 Sham 0/41 | rTMS 1/96 Sham 1/57 | rTMS 5/20 Sham 0/10 | rTMS 3/20 Sham 0/10 | rTMS 4/168 Sham 5/127 |
Abbreviations: Bi, bilateral; rTMS, repetitive transcranial magnetic stimulation; Uni, unilateral.
Includes anger.
Includes racing thoughts.
Includes confusion.
Combined rTMS with and without venlafaxine.
Adverse events reported by group (100% motor threshold, 90% motor threshold, sham).