Table 2.
Patient 1 | ||||
---|---|---|---|---|
Baseline clinical characteristics | Brain MRI and clinical course | |||
Age at PML diagnosis (years) | 78 | |||
Sex | Male | |||
Underlying diagnosis | Non-Hodgkin lymphoma in remission | |||
Latency initial hematologic malignancy and PML | 9 months | |||
Immunosuppressive treatment | Rituximab, bendamustine | |||
Neurological deficits | Left-sided facial nerve palsy, psychomotor slowing, dysarthria | Left-sided facial nerve palsy, psychomotor slowing, dysarthria | Left-sided facial nerve palsy, psychomotor slowing, paresis of left hand, dysarthria, dysphagia | Left-sided facial nerve palsy, psychomotor slowing, left hemiparesis, dysarthria, dysphagia |
Modified Rankin Scale | 3 | 3 | 4 | 4 |
Total no. of pembrolizumab infusions | 4 |
MRI, magnetic resonance imaging; PML, progressive multifocal leukoencephalopathy.