Table 3.

Clinical characteristics, brain MRI, and clinical course of patient 2 during pembrolizumab treatment. The right frontal signal changes are due to brain biopsy.

Patient 2
Baseline clinical characteristics		Brain MRI and clinical course
Age at PML diagnosis (years)	73
Sex	Male
Underlying diagnosis	Non-Hodgkin lymphoma, relapsing
Latency initial hematologic malignancy and PML	22 years
Immunosuppressive treatment	Mitoxantrone, melphalan, prednisone
Neurological deficits	Left-sided facial nerve palsy, left-sided hand extensor paresis	Left-sided facial nerve palsy, moderate hemiparesis on the left side	Minimal left-sided hand extensor paresis	No neurological deficits
Modified Rankin Scale	2	2	1	0
Total no. of pembrolizumab infusions	3

MRI, magnetic resonance imaging; PML, progressive multifocal leukoencephalopathy.