e-Table 11.
Characteristics of BODE group (score 0-2) compared to equally-sized MLMP-COPD mortality risk group
| BODE group | Model group | p-value | |
|---|---|---|---|
| No. | 1589 | 1589 | |
| Age, mean (SD), y | 63.44 (8.57) | 60.31 (8.11) | <0.001 |
| Race, African American, No. (%) | 166 (10.4) | 233 (14.7) | <0.001 |
| Sex, female, No. (%) | 603 (37.9) | 696 (43.8) | 0.001 |
| Total dead, No. (%) | 216 (13.6) | 163 (10.3) | 0.004 |
| Days followed up, median (IQR) | 2530.00 [2189.00, 2895.00] | 2530.00 [2199.00, 2834.00] | 0.885 |
| BODE, median (IQR) | 1.00 [0.00, 2.00] | 1.00 [0.00, 2.00] | <0.001 |
| 6-minute walk distance, mean (SD), ft | 1458.03 (273.13) | 1471.93 (289.34) | 0.164 |
| FEV1 % predicted, median (IQR) | 65.00 [55.20, 71.60] | 63.90 [53.80, 71.50] | 0.064 |
| mMRC dyspnea score, No. (%) | <0.001 | ||
| 0 | 623 (39.2) | 536 (33.7) | |
| 1 | 608 (38.3) | 430 (27.1) | |
| 2 | 286 (18.0) | 311 (19.6) | |
| 3 | 72 (4.5) | 229 (14.4) | |
| 4 | 0 (0.0) | 83 (5.2) | |
| FEV1/FVC ratio, median (IQR) | 0.57 [0.48, 0.63] | 0.58 [0.49, 0.64] | 0.002 |
| FEF25%-75%, median (IQR), L | 0.68 [0.47, 0.95] | 0.69 [0.48, 0.97] | 0.201 |
| Resting SaO2, median (IQR) | 96.00 [94.00, 97.00] | 96.00 [95.00, 97.00] | 0.003 |
| Exacerbation frequency, mean (SD), No./yr | 0.41 (0.84) | 0.40 (0.85) | 0.866 |
| Pack-years cigarette smoking, median (IQR) | 44.00 [32.20, 60.00] | 42.00 [31.00, 57.90] | 0.002 |
| BMI, mean (SD), kg/mˆ2 | 27.75 (5.01) | 28.60 (5.91) | <0.001 |
| Severe Exacerbations, No. (%) | 156 (9.8) | 143 (9.0) | 0.466 |
| PA:A ratio, mean (SD) | 0.88 (0.13) | 0.86 (0.12) | 0.009 |
| Pi10, mean (SD) | 3.90 (0.37) | 3.84 (0.33) | <0.001 |
| Diabetes, No. (%) | 149 (9.4) | 140 (8.8) | 0.622 |
| % LAA < -950 HU, median (IQR) | 6.24 [2.21, 14.67] | 5.02 [1.78, 13.28] | 0.001 |