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. 2021 Jan 10;159(5):1747–1757. doi: 10.1016/j.chest.2020.12.051

Figure 1.

Figure 1

A-C, Prediction model of nonsevere asthma exacerbation. Interpretation of model built with gradient boosting machine algorithm. A, Top 20 risk factors, with iCS + inhaled LABA or HDiCS being the most important one: present (pink) increased the risk of exacerbation, whereas absent (blue) decreased it. B, C, Plots of relative risk (log SHAP value) and age (B) and BMI (C) showed that advanced age and higher BMI associated with higher risk of nonsevere asthma exacerbation. †Race: 0 = other, 1 = White, 2 = Black, and 3 = Asian. ‡Smoking status: 0 = other, 1 = never smoker, 2 = active smoker, and 3 = former smoker. Tx variables were: 1 = present or 0 = absent. Lab variables were the value of the tests. GERD = gastroesophageal reflux disease; HDiCS = high-dose inhaled corticosteroid; Hgb = hemoglobin; iCS = inhaled corticosteroid; Lab = laboratory; LABA = long-acting inhaled β-agonist; SHAP = shapley additive explanation; Tx = treatment.