Table 3.
Group | Baseline | Endpoint | |||||||
---|---|---|---|---|---|---|---|---|---|
Active (n = 20) (95%CI) | Sham (n = 20) (95%CI) | Active (n = 18) (95%CI) | Sham (n = 20) (95%CI) | MCDb | t | p | 95%CI | ESc | |
SWM Errorsa | 23 ± 1.7 (19.6–26.5) | 23 ± 1.7 (19.6–26.6) | 19.3 ± 1.9 (15.6–23.1) | 20.2 ± 1.9 (16.4–23.9) | 0.79 | 2,67 = 0.24 | 0.8 | −5.8-7.3 | 0.04 |
BRIEF MCIa | 71.7 ± 1.4 (68.8–74.6) | 71.5 ± 1.4 (68.6–74.4) | 61.8 ± 1.6 (58.6–64.9) | 64 ± 1.6 (68.6–74.4) | 2.5 | 2,68 = 0.96 | 0.3 | −2.7-7.7 | 0.28 |
BRIEF-MCI = Behavioral Rating Inventory for Executive Function Metacognition Index, SWM Errors = spatial working memory total errors score, MCD = Mean Change Difference, ES = Effect Size, CI=Confidence Interval.
Values presented as Mean ± SE are adjusted for baseline score and IQ.
Difference in mean change from baseline to endpoint were calculated by subtracting the adjusted mean score at follow-up from the adjusted mean score at baseline for each group (active-sham).
Cohen’s d effect sizes were calculated by subtracting the adjusted mean score at follow-up from the adjusted mean score at baseline for each group, then dividing the result by the pooled baseline SDs.