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. 2021 Mar 29;10:2. Originally published 2021 Jan 5. [Version 2] doi: 10.12688/f1000research.27089.2

Table 5. Presence or absence of CCD and comparison between reported clinical cross-reactivities and obtained cross-reactivities.

Allergens Absence
of CCD
Clinical cross-
reactivity
Demonstrated
cross
reactivities
obtained
References
Group A
Ves m 1 No report With Dol m 1, Ves
v 1
This Group has
to identity of
79%
King, Te Piao, et al. “Yellow Jacket Venom Allergens,
Hyaluronidase and Phospholipase: Sequence Similarity
and Antigenic Cross-Reactivity with Their Hornet and Wasp
Homologs and Possible Implications for Clinical Allergy.”
Journal of Allergy and Clinical Immunology, vol. 98, no. 3,
1996, pp. 588–600, doi: 10.1016/S0091-6749(96)70093-3.
Ves s 1 No report _____
Ves v 1 Absence With Dol m 1, Pol
d 1
Group B
Api c 1 No report _____ This Group has
to identity of
64% without
api c 1
- Jakob, Thilo, Julian Köhler, et al. “Comparable IgE Reactivity
to Natural and Recombinant Api m 1 in Cross-Reactive
Carbohydrate Determinant-Negative Patients with Bee
Venom Allergy.” Journal of Allergy and Clinical Immunology,
vol. 130, no. 1, 2012, pp. 276–78, doi:: 10.1016/j.jaci.2012.03.048.
- Müller, U, et al. IgE to Recombinant Allergens Api m 1 , Ves
v 1 , and Ves v 5 Distinguish Double Sensitization from
Crossreaction in Venom Allergy. 2012, doi: 10.1111/j.1398-9995.2012.02847.x.
Api m 1 Present With Ves v 1, Ves s 1
Bom p 1 No report _____
Bom t 1 No report _____
Group C
Sol i 1 Present Poly p 1, Ves m 1,
Ves v 1, Dol m 1
This Group has
to identity of
23%
- Perez-Riverol, Amilcar, et al. “Venoms of Neotropical Wasps
Lack Cross-Reactive Carbohydrate Determinants Enabling
Reliable Protein-Based Specific IgE Determination.” Journal
of Allergy and Clinical Immunology, vol. 141, no. 5, 2018, pp.
1917–20, doi:10.1016/j.jaci.2017.12.990.
- Hoffman, Donald R., et al. “Sol i 1, the Phospholipase
Allergen of Imported Fire Ant Venom.” Journal of Allergy
and Clinical Immunology, vol. 115, no. 3, 2005, pp. 611–16,
doi: 10.1016/j.jaci.2004.11.020.
Sol i 2 No report _____
Sol s 2 No report _____
Group D
Pol d 1 Absence Poly p 1, Ves s 1 This Group has
to identity of
64%
- Perez-Riverol, Amilcar, Luís Gustavo Romani Fernandes,
et al. “Phospholipase A1-Based Cross-Reactivity
among Venoms of Clinically Relevant Hymenoptera
from Neotropical and Temperate Regions.” Molecular
Immunology, vol. 93, Elsevier, 2018, pp.
87–93.
- Monsalve, R. I., et al. “Component-Resolved Diagnosis of
Vespid Venom-Allergic Individuals: Phospholipases and
Antigen 5s Are Necessary to Identify Vespula or Polistes
Sensitization.” Allergy: European Journal of Allergy and Clinical
Immunology, vol. 67, no. 4, 2012, pp. 528–36, doi:,
doi: 10.1111/j.1398-9995.2011.02781.x
Pol a 1 No report Poly p 1
Poly p 1 No report Sol I 1, Pol d 1, Pol a
1, Ves v 1
Dol m 1 Absence Ves v 1, Ves m 1
Vesp c 1 No report _____