Table 2. Mixed-Effects Logistic Regression Analysis of Outcomes^a.

Model	In-hospital death			Favorable discharge
	OR (95% CI)	SE	P value	OR (95% CI)	SE	P value
Unadjusted model	5.95 (5.58-6.35)	0.20	<.001	0.31 (0.30–0.33)	0.01	<.001
Adjusted model 1b	5.17 (4.83-5.53)	0.18	<.001	0.33 (0.31–0.35)	0.01	<.001
Adjusted model 2c	3.57 (3.15-4.05)	0.23	<.001	0.49 (0.44-0.54)	0.03	<.001

Abbreviations: EVT, endovascular thrombectomy; IS, ischemic stroke; IV, intravenous; OR, odds ratio.

^aAnalysis of 5517 patients with IS and COVID-19 discharged between April and December 2020 compared with control group of 165 912 patients with IS discharged in 2019.

^bAdjusted for patient age, sex, and race/ethnicity; presence of diabetes, congestive heart failure, obesity, and smoking; and Elixhauser Comorbidity Index score.

^cAdjusted for patient age, sex, and race/ethnicity; presence of diabetes, congestive heart failure, obesity, and smoking; Elixhauser Comorbidity Index score; National Institutes of Health Stroke Scale score; and receipt of IV alteplase and EVT. This model included 2314 patients with IS and COVID-19 discharged between April and December 2020 compared with the control group of 92 751 patients with IS discharged in 2019.