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. 2021 May 18;373:n1022. doi: 10.1136/bmj.n1022

Table 2.

Hepatitis C virus antibody screening at four months

Substudy Completed antibody screening, n (%; 95% CI)* Difference, % (95% CI) P value†
Substudy A: opt in or opt out
 Letter only (n=813) 156 (19.2; 16.5 to 21.9) 23.9 (19.6 to 28.2) <0.001
 Letter+laboratory order (n=829) 357 (43.1; 39.7 to 46.4)
Substudy B: content
 Usual care messaging (n=9828) 1431 (14.6; 13.9 to 15.3) −1.0 (−1.9 to 0.0) 0.06
 Behavioral messaging (n=9833) 1341 (13.6; 13.0 to 14.3)
Substudy B: communication mode
 Mailed letter (n=1897) 337 (17.8; 16.0 to 19.5) −4.0 (−5.8 to −2.1) <0.001
 Patient portal message (n=9498) 1313 (13.8; 13.1 to 14.5)
*

Includes only patients screened using antibody testing.

P value less than 0.05 was threshold for statistical significance using χ2 test of proportions.