Figure 4.

Cell apoptosis rate in the CBATO and ATO groups in liver cancer cells. Cell apoptosis rate in HepG2 cells at (A) 24 h and (B) 48 h between the CBATO and ATO groups. Cell apoptosis rate in MHCC97H cells at (C) 24 h and (D) 48 h between the CBATO and ATO groups. Comparison between the CBATO and ATO groups was determined by t-test, P<0.05 was considered as significant. Comparison among various concentrations within a group was determined by one-way ANOVA followed by multiple comparisons test (Tukeys test), P<0.05 was considered as significant, the statistical significance was not presented in the figure but described in the Result section. ATO, arsenic trioxide; CBs, CalliSphere beads; NS, no significance.