Table 2.
Estimated Bed-day Costs
| Opportunity cost, mean (SD) | Accounting cost, mean (SD) | |||||||
|---|---|---|---|---|---|---|---|---|
| Per infection | R | S | R-Sa | Per infection | R | S | R-Sa | |
| Bloodstream infections | ||||||||
| S. aureus | 909.1 (97.6) | 1347.7 (144.4) | 844.6 (91.1) | 503.2 (172.9) | 9877.8 (999.8) | 14 617.7 (1481.5) | 9194.8 (926.4) | 5422.9 (1744.2) |
| E. faecium | 573.9 (68.4) | 318.0 (36) | 760.3 (83.1) | −442.3 (90.8) | 6236.9 (722.8) | 3448.6 (366.1) | 8253.6 (838.7) | −4805.0 (916.7) |
| E. coli | 399.7 (45.7) | 403.6 (43.8) | 401.0 (44.6) | 2.7 (62.7) | 4341 (465.4) | 4402.5 (449.9) | 4350.7 (453.2) | 51.8 (634.2) |
| K. pneumoniae | 526.3 (57.4) | 1250.1 (137.3) | 496.5 (53.9) | 753.5 (147.9) | 5730.3 (589.7) | 13 597.6 (1415.1) | 5391.6 (554.3) | 8206.1 (1516.8) |
| P. aeruginosa | 571.9 (62.3) | 898.5 (106.4) | 555.9 (60.7) | 342.6 (123.1) | 6224.3 (632.1) | 9774.1 (1104.3) | 6055.2 (617.7) | 3718.9 (1262.2) |
| Urinary infections | ||||||||
| S. aureus | 257.4 (30.5) | 415.8 (52.3) | 235.3 (27.8) | 180.5 (59.6) | 2793.3 (309.1) | 4508.6 (539.1) | 2555.5 (285.4) | 1953.1 (608.5) |
| E. faecium | 184.1 (23.3) | 244.9 (29.7) | 152.3 (20.3) | 92.6 (36) | 2001.6 (242.7) | 2662.3 (307.8) | 1652.3 (210.8) | 1010.0 (370.6) |
| E. coli | 87.5 (15.1) | 173.8 (22.5) | 90.6 (15.2) | 83.2 (27.3) | 949.4 (161) | 1891.9 (229.4) | 986.4 (162.4) | 905.5 (283.5) |
| K. pneumoniae | 54.9 (13.1) | 418.6 (54.3) | 36.7 (12.5) | 381.8 (55.7) | 597.5 (140.7) | 4560.4 (571.4) | 400.0 (137.2) | 4160.3 (588.9) |
| P. aeruginosa | 145.8 (20) | 348.7 (39.6) | 139.1 (19.1) | 209.5 (44) | 1584.2 (209.8) | 3784.8 (411.6) | 1511.5 (196.5) | 2273.3 (457.8) |
| Respiratory infections | ||||||||
| P. aeruginosa | 486.4 (53.5) | 412.4 (46.1) | 498.8 (54.6) | −86.4 (71.6) | 5294.8 (545.5) | 4475.8 (471.2) | 5421.9 (561.3) | −946 (734.2) |
Data are represented as opportunity and accounting costs associated with health care–associated infections in Queensland (2012–2016).
Abbreviations: E. coli, Escherichia coli; E. faecium, Enterococcus faecium; K. pneumoniae, Klebsiella pneumoniae; P. aeruginosa, Pseudomonas aeruginosa; R, resistant; S, sensitive; S. aureus, Staphylococcus aureus; SD, standard deviation.
aCost of resistance calculated as the difference in cost between a resistant and sensitive infection.