Koju 2015.

Study characteristics
Methods	RCT
Participants	50 women for elective CD under spinal
Interventions	Intervention: 5‐HT3antagonist (A) Ondansetron 4 mg, IV before spinal N = 25 Comparison: placebo Normal saline. N = 25
Outcomes	PONV on 4 point scale every 15 in for 4 hours, then at 4, 8 and 24 hours
Notes	Setting: Patan Hospital, Patan, Lalitpur, Nepal. Dates: August 2008 to January 2009 Funding source: not reported. Declaration of interest: state no conflict of interest both financial and non‐financial.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Unspecified:quote: "randomly allocated"
Allocation concealment (selection bias)	Unclear risk	Only reports that women and clinicians unaware of allocation
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Nurse drew up drugs, Dr administered
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not described
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	No dropouts
Selective reporting (reporting bias)	Unclear risk	Resident (junior) doctors performed data collection
Other bias	Unclear risk	No baseline imbalance