Lee 2002.

Study characteristics
Methods	RCT
Participants	Inclusion criteria: Women undergoing elective CS under spinal anaesthesia. N = 60 women randomised Exclusion criteria:
Interventions	Intervention 1: 5HT3 antagonist (Comparison 1) Granisetron 10 ug/kg N = 15 Intervention 2: 5HT3 antagonist (Comparison 1) Granisetron 20 ug/kg N = 15 Intervention 3: 5HT3 antagonist (Comparison 1) Granisetron 30 ug/kg N = 15 Comparator: placebo N = 15
Outcomes	VAS pain scores, emetic episodes, emesis scores, side effects
Notes	Setting: Samsung Cheil Hospital, Seoul, South Korea. Dates: not reported. Funding source: not reported. Declaration of interest: not reported. Full paper in English. There were no data for this review
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: "randomised according to computerised list"
Allocation concealment (selection bias)	Unclear risk	Unrelated anaesthetist prepared syringes
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	As above
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Quote: "post operative emetic scores were recorded by anesthesiologist blinded to which antiemetic each patient had received"
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	Not clear if any data incomplete/missing
Selective reporting (reporting bias)	Unclear risk	outcomes appear to be consistent with methods, but we did not assess the trial protocol
Other bias	Unclear risk	Nil apparent