Lussos 1992.

Study characteristics
Methods	RCT
Participants	42 women undergoing elective CS under spinal anaesthesia, without treatment of nausea and vomiting in the week before surgery, diabetes or uteroplacental insufficiency.
Interventions	Intervention: dopamine antagonist (Comparison 2) 10 mg metoclopramide. N = 21. Comparison: placebo 2 mL normal saline. N = 21.
Outcomes	Nausea and vomiting pre and postdelivery.
Notes	Setting: Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Dates: not reported Funding source: not reported. Declaration of interest: not reported.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Not described.
Allocation concealment (selection bias)	Unclear risk	Not described.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Not described
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Not described
Incomplete outcome data (attrition bias) All outcomes	Low risk	All included.
Selective reporting (reporting bias)	Unclear risk	We did not assess the trial protocol.
Other bias	Low risk	Similar baseline characteristics.