Yazigi 2002.

Study characteristics
Methods	RCT
Participants	100 ASA 1‐2 women undergoing elective CS.
Interventions	Intervention: 5‐HT3antagonist (Compaeison 1) Ondansetron 8 mg IV. N = 50. Comparison: placebo Normal saline. N = 50.
Outcomes	Pruritis, nausea, vomiting, pain, side effects.
Notes	Setting: Hotel‐Dieu de France University Hospital, Beirut, Lebanon. Dates: not reported. Funding source: not reported. Declaration of interest: not reported. This study currently provides no data for the review because the outcomes are reported as combined "Nausea and Vomiting". We have written to the authors requesting separated data.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated.
Allocation concealment (selection bias)	Unclear risk	Not described.
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Quote: "Drug solutions were given according to a double blinded protocol"
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Quote: "Assessment was made by an anesthesia resident who was blinded to the treatment groups”.
Incomplete outcome data (attrition bias) All outcomes	Low risk	None described.
Selective reporting (reporting bias)	Unclear risk	Outcomes in methods reported in the results but we did not assess the trial protocol.
Other bias	Unclear risk	Similar baseline characteristics but insufficient methodology reported to be sure of no further bias.