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. 2021 May 12;22(1):524. doi: 10.3892/ol.2021.12785

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Copyright: © Fa et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — DNM3 is expressed at significantly low levels in human cervical cancer tissues and cells compared with normal cervical tissues and cells. (A) Bioinformatics analysis of the expression profile of DNM3 in cervical squamous cell carcinoma and endocervical adenocarcinoma and normal tissues. All data are from the GEPIA online database. (B) Immunohistochemistry staining of DNM3 protein in human cervical cancer tissue specimens. (C) Overall survival curve of the human cervical cancer patients with different DNM3 expression levels. All data are from the GEPIA online database. (D) The endogenous expression of DNM3 in cervical carcinoma cell lines (Caski, SiHa, Hela and C33A) was higher compared with that in the normal cervical cell line H8, as determined by RT-qPCR. (E) Immunofluorescence staining for DNM3 protein in C33A and SiHa cells (magnification, ×400). *P<0.05, **P<0.01. DNM3, dynamin 3; GEPIA, Gene Expression Profiling Interactive Analysis; RT-q, reverse transcription quantitative; t, tumor; n, normal; HR, hazard ratio.