Table 2.
Risk variables for regional lymph nodes metastasis determined by univariate and multivariate logistic regression analyses
| Characteristics | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| OR | P value | 95% CI | OR | P value | 95% CI | |
| Age (years) | ||||||
| ≤ 60 | Reference | Reference | ||||
| > 60 | 0.82 | 0.096 | 0.65–1.04 | 0.85 | 0.199 | 0.66–1.09 |
| Race | ||||||
| White | Reference | Reference | ||||
| Black | 1.16 | 0.335 | 0.86–1.57 | 0.98 | 0.883 | 0.71–1.35 |
| Othersa | 1.25 | 0.325 | 0.80–1.95 | 1.12 | 0.639 | 0.70–1.78 |
| Marital status | ||||||
| Unmarried | Reference | Reference | ||||
| Married | 0.73 | 0.010 | 0.58–0.93 | 0.80 | 0.089 | 0.62–1.03 |
| Unknown | 0.83 | 0.560 | 0.43–1.58 | 0.95 | 0.875 | 0.48–1.87 |
| Grade | ||||||
| I | Reference | Reference | ||||
| II | 2.07 | 0.119 | 0.83–5.16 | 1.83 | 0.208 | 0.71–4.68 |
| III | 3.65 | 0.003 | 1.56–8.54 | 2.69 | 0.026 | 1.12–6.46 |
| IV | 4.36 | 0.003 | 1.63–11.63 | 3.05 | 0.031 | 1.10–8.45 |
| Laterality | ||||||
| Right | Reference | Reference | ||||
| Left | 0.82 | 0.094 | 0.65–1.04 | 0.79 | 0.058 | 0.62–1.01 |
| ER status | ||||||
| Negative | Reference | Reference | ||||
| Positive | 1.49 | 0.007 | 1.12–1.98 | 1.60 | 0.006 | 1.14–2.23 |
| PR status | ||||||
| Negative | Reference | Reference | ||||
| Positive | 1.08 | 0.644 | 0.77–1.52 | 0.97 | 0.870 | 0.65–1.44 |
| Tumor size | ||||||
| ≤ 2 cm | Reference | Reference | ||||
| > 2 cm and ≤ 5 cm | 2.39 | < 0.001 | 1.68–3.39 | 2.19 | < 0.001 | 1.54–3.13 |
| > 5 cm | 6.10 | < 0.001 | 4.18–8.91 | 5.51 | < 0.001 | 3.74–8.11 |
OR Odds ratios, CI Confidential interval, ER Estrogen receptor, PR progesterone receptor
aIncludes: American Indian, native Alaskan and Asian, Pacific Islander