Table 4.

Univariate and Multivariable Cox Regression Analysis for Overall Survival

Variable	Overall survival
	Univariate analysis		Multivariate analysis
	HR (95%CI)	P	HR (95%CI)	P
Gender: female/male	1.13 (0.53–2.43)	0.753
Age at operation (≥ 65 years/< 65 years)	2.12 (0.98–4.60)	0.056
Preoperative chemotherapy (yes/no)	0.36 (0.13–0.92)	0.033	0.55 (0.22–1.39)	0.204
T stage (T4/T3)	1.61 (0.73–3.54)	0.235
N stage
N0	Reference	Reference
N1	1.29 (0.57–2.94)	0.545
N2	2.26 (0.71–7.16)	0.167
Site of original (rectum/colon)	1.48 (0.63–3.51)	0.373
Histology (mucinous/adenocarcinoma)	2.05 (0.96–4.40)	0.065
Preoperative CEA level (≥ 5 ng/ml/< 5 ng/ml)	1.68 (0.78–3.58)	0.183
Liver metastases (yes/no)	1.24 (0.50–3.08)	0.648
HIPEC regimen (lobaplatin/non-lobaplatin)	1.38 (0.62–3.05)	0.427
Presence of ascites (yes/no)	1.20 (0.55–2.60)	0.650
PCI score (≥ 12/< 12)	2.98 (1.41–6.32)	0.004	1.49 (0.61–3.66)	0.381
CC score (2–3/0–1)	4.20 (1.89–9.36)	< 0.001	2.99 (1.14–7.84)	0.026
Grade 3–4 postoperative complication (yes/no)	1.62 (0.74–3.57)	0.229