Figure 1. Flow chart of the study. The study was carried out in Pediatric Brain Tumor Atlas (CBTTC) cohort. The training cohort was used to identify prognostic genes. The LASSO regression model was used to establish a prognostic signature based on the prognostic genes. The prognosis analysis was validated in the validation cohort. LASSO: least absolute shrinkage and selection operator Cox regression model; ROC: receiver operating characteristic; TICs: tumor-infiltrating immune cells.