Table 2.
Summary of groups present in current study
| Total * (N = 519) | HIV-infected (N = 284) | HIV-uninfected (N = 235) | P value | |
|---|---|---|---|---|
| TB cases—no. (%) | 117 (22.5) | 66 (23.2)* | 51 (21.7) | 0.68 |
| Confirmed PTB | 6 (1.2) | 3 (1.1) | 3 (1.3) | 0.26 |
| Confirmed EPTB a | 2 (0.4) | 2 (0.7) | – | – |
| Unconfirmed PTB | 108 (20.8) | 60 (21.1) | 48 (20.4) | – |
| MTB infection b | 73 (14.1) | 45 (15.8) | 28 (11.9) | 0.10 |
| No MTB infection c | 35 (6.7) | 15 (5.3) | 20 (8.5) | – |
| Unconfirmed EPTB d | 3 (0.6) | 3 (1.1) | – | – |
| Unlikely TB—no. (%) | 402 (77.5) | 218 (76.8) | 184 (78.3) | – |
| MTB infection | 53 (10.2) | 32 (11.3) | 21 (8.9) | 0.33 |
| No MTB infection e | 349 (67.3) | 186 (65.5) | 163 (69.4) | – |
| Died | 9 (1.7) | 7 (2.5) | 2 (0.9) | 0.16 |
*Two infants diagnosed with both unconfirmed EPTB and unconfirmed PTB were counted once in this total
aBoth of these EPTB cases were diagnosed as TB lymphadenitis
bMTB infection = TST-positive (induration of ≥ 5 mm for HIV-infected infants and ≥ 10 mm for HIV-uninfected infants)
cNo MTB infection = TST-negative (induration of < 5 mm for HIV-infected infants and < 10 mm for HIV-uninfected infants)
dTwo infants were diagnosed with both unconfirmed TB lymphadenitis and unconfirmed PTB, and the third was diagnosed with TB meningitis
eTST-negative or no TST result available for infants not suspected of TB who did not reach a protocol-designated visit for TST performance (parent study weeks 96, 144, 196)