Alterations in bacterial and fungal communities of active steroid-naïve subjects achieving remission after topical swallowed steroid (TSS) therapy. A, Heatmap of bacterial composition. The colors represent the relative abundance of a taxon. B, Principle coordinate analysis of unweighted UniFrac distances between samples. The lines connect the pre- and post-TSS samples from the same subject. C, Relative abundances of Actinobacillus and Haemophilus. D, Heatmap of fungal composition. The colors represent PicoGreen-corrected operational taxonomic unit (OTU) abundances. E, Fraction of samples where fungal genus Candida is present. F, PicoGreen-corrected OTU abundances of Candida and Cladosporium. Lines connect pre- and post-TSS samples from the same subjects