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. Author manuscript; available in PMC: 2022 Feb 1.
Published in final edited form as: Contemp Clin Trials. 2020 Dec 11;101:106246. doi: 10.1016/j.cct.2020.106246

Table 3.

Eligibility criteria.

Inclusion criteria Exclusion criteria
  • Physician-diagnosed asthma for at least 1 year

  • Age 18–75 years

  • African American/Black or Hispanic/Latinx based on self-identification

  • Ability to provide informed consent

  • Clinical history consistent with asthma for >1 year

  • Prescribed daily ICS with or without additional maintenance therapies

  • ACT score of ≤19 OR a patient-reported history of ≥1 asthma exacerbation in the past year requiring systemic corticosteroid use

  • Life expectancy <1 year

  • Known allergy to beclomethasone dipropionate

  • Chronic Obstructive Pulmonary Disease (COPD) or other chronic lung disease other than asthma, with the exception of the following:
    • Diagnosis of COPD in a never smoker without any other lung disease or any other disease that might cause airway obstruction
    • Diagnosis of COPD in a former smoker with normal pulmonary function tests (PFTs)a after the patient quit smoking
    • Diagnosis of COPD in a current smoker with normal PFTsa in the past 24 months
    • Diagnosis of COPD in a current or former smoker with obstruction on PFTs, but normal diffusing capacity in the past 24 months AND demonstrated forced expiratory volume in one second (FEV1) reversibility to bronchodilator of 12% or more at any time
  • Asthma exacerbation in the past month requiring use of systemic corticosteroid; visit to the doctor’s office, ED or urgent care; or overnight hospitalization

  • Regular systemic corticosteroid use (daily or every other day) for any reason

  • Use of biologics for asthma (injection or infusion), unless the patient has been on a stable dose of a biologic for at least 6 months AND:
    • Had an asthma exacerbation at least 2 months after starting the biologic, OR
    • Has a current ACT score of ≤19
  • Bronchial thermoplasty within the past 6 months

  • Another person living in the same household already enrolled in the study

a

Normal PFTs defined as: FEV1 > 80% predicted, FEV1/forced vital capacity (FVC) ≥70%, and diffusing capacity for carbon monoxide (DLCO) ≥80% predicted.