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. 2021 Jan 30;24(5):400–408. doi: 10.1093/ijnp/pyab003

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© The Author(s) 2021. Published by Oxford University Press on behalf of CINP.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Cytosol and membrane protein expression of protein kinase C (PKC) isozymes. Representative blots of different PKC isozymes (PKC α, βI, βII, γ, δ, and ε) in (a) cytosol and (b) membrane fractions, and the histograms are presenting corresponding percentage change in protein expression of these PKC isozymes in (c) cytosol and (d) membrane fractions of prefrontal cortex (PFC) region of postmortem brains of normal control (NC), depressed suicide (DS), and depressed nonsuicide (DNS) subjects. Values are represented as mean percentage change ± standard error of the mean (SEM). *(* = ≤0.05, ** = ≤0.01, *** = ≤0.001) and + (+ = ≤0.05, ++ = ≤0.01, +++ = ≤0.001) represent the statistically significant difference between NC-DS and NC-DNS, respectively. The target protein expression was normalized by using β-actin as a house keeping gene.