Table 3.

Associations between HRQoL at 12-months follow-up and the other outcome variables; BMI, RTWSE, WAS, DWP and work absence, adjusted for the background variables. Unadjusted and adjusted multiple regression analyses

	Unadjusted analysis:			Final analysis:
	B a	95% CI	p values	B	95% CI	p values
Age	0.12	−0.02: 0.27	0.100
Gender
Male	0			0
Females	−0.38	−3.23: 2.47	0.792	2.07	0.031:4.10	0.047
Sick leave diagnosis			0.015
MS b	0
EMD c	4.89	1.45: 8.32	0.006
All other d	3.2	0.09: 6.31	0.044
Educational level			0.267
Collage/university (< 14 years)	2.26	−0.74: 5.25	0.137
High school (> 13 years)	0
Elementary school (> 10 years)	2.59	−2.04: 7.22	0.268
HRQoL (baseline)	0.65	0.44: 0.86	< 0.001	0.73	0.53: 0.94	< 0.001
BMI e	−0.59	−0.10: −0.05	0.031	−0.34	− 0.65:-0.04	0.029
RTWSE e	0.04	0.01: 0.07	0.021	0.02	0.004: 0.04	0.023
WAS e	0.86	0.43: 1.34	< 0.001	0.91	0.55: 1.28	< 0.001
DWP e	0.017	0.01:0.05	0.242	−0.019	−0.04:0.001	0.060
Work absence f	−0.02	−0.03: − 0.01	0.001	−0.01	− 0.02: − 0.002	0.020

Univariate analyses. Variables were included and excluded according to F-tests for changes in R2 marked with bold and further included in the final analyses

Multiple regression analysis: Final analyses are controlled for the effect of background variables and HRQoL baseline

^a Unstandardized regression coefficient (B)

^b Musculoskeletal diagnosis

^c Endocrine, metabolic, and nutritional diagnosis

^d All other reported diagnosis

^e Value of change from baseline to 12-months

^f Work absence, measured as the number of days from baseline to 12-month follow-up

In the final analyses; statistically significant p values (≤ 0.05) marked in bold

R² Final analysis = 71,8 F = 17,48