Table 2.

Univariable and multivariable Cox proportional hazards regression models of NEFM expression with clinicopathological features in TCGA BRCA cohort

Characteristics	Univariate			Multivariate
	HR	CI95	p	HR	CI95	p
Subgroup	1.03	0.89–1.2	0.648
Stage	1.8	1.38–2.35	< 0.001	1.83	1.34–2.51	< 0.001
NEFM	0.53	0.36–0.8	0.002	0.58	0.36–0.95	0.031
Age	1.03	1.02–1.05	< 0.001	1.03	1.01–1.05	0.001
ER	0.56	0.37–0.85	0.007	0.62	0.3–1.28	0.198
PR	0.6	0.4–0.9	0.013	0.67	0.33–1.37	0.271
HER2	1.75	1.09–2.8	0.021	1.61	0.96–2.69	0.071

HR: hazard ratio; CI 95: 95% confidence interval; subgroup: luminal A, luminal B, positive HER2, basal, normal; stage: I, II, III, IV; NEFM: low or high expression by median. Age, ER, PR, HER2 was divided into two groups according to the median, respectively. Significant p values < 0.05 are in bold