Table 5.
MHC molecules | NEFM expression | NEFM DNA methylation | ||
---|---|---|---|---|
TISIDB rho, n = 1100 | p | TISIDB rho, n = 785 | p | |
B2M | − 0.11 | 0.00025 | − 0.287 | 2.85e−16 |
HLA-A | − 0.093 | 0.00205 | − 0.3 | 1.23e−17 |
HLA-B | − 0.089 | 0.00388 | − 0.315 | 1.58e−19 |
HLA-C | − 0.077 | 0.0107 | − 0.212 | 2.35e−09 |
HLA-DMA | 0.058 | 0.0561 | − 0.405 | < 2.2e−16 |
HLA-DMB | 0.03 | 0.313 | − 0.414 | < 2.2e−16 |
HLA-DOA | 0.156 | 2.16e−07 | − 0.458 | < 2.2e−16 |
HLA-DOB | 0.034 | 0.266 | − 0.503 | < 2.2e−16 |
HLA-DPA1 | 0.084 | 0.00511 | − 0.407 | < 2.2e−16 |
HLA-DPB1 | 0.153 | 3.46e−07 | − 0.435 | < 2.2e−16 |
HLA-DQA1 | 0.061 | 0.0446 | − 0.398 | < 2.2e−16 |
HLA-DQA2 | 0.057 | 0.058 | − 0.294 | 5.78e−14 |
HLA-DQB1 | 0.081 | 0.00747 | − 0.352 | < 2.2e−16 |
HLA-DRA | 0.061 | 0.0447 | − 0.434 | < 2.2e−16 |
HLA-DRB1 | 0.089 | 0.00329 | − 0.39 | < 2.2e−16 |
HLA-E | 0.05 | 0.0991 | − 0.484 | < 2.2e−16 |
HLA-F | − 0.028 | 0.358 | − 0.377 | < 2.2e−16 |
HLA-G | − 0.04 | 0.189 | − 0.231 | 6.32e−11 |
TAP1 | − 0.204 | 8.63e−12 | − 0.267 | 3.39e−14 |
TAP2 | − 0.176 | 4.89e−09 | − 0.381 | < 2.2e−16 |
TAPBP | − 0.143 | 1.91e−06 | − 0.057 | 0.109 |
Significant p value < 0.05 is in bold