Fig. 1.

Study design and definition of triple-negative breast cancer (TNBC) rapid vs. late relapse. a REMARK diagram. b Proportion of distant metastasis-free survival (DMFS) events per year after diagnosis among evaluable dataset. ‘Rapid relapse’ was defined as DMFS events within the 2 years of diagnosis and ‘late relapse’ DMFS events beyond 2 years. c-e Kaplan-Meier diagram of DMFS in study cohort reflecting TNBC group definitions (c), compared with DMFS by intrinsic subtype approaches PAM50 subtype (d), and Lehmann TNBC subtype (e). P-value indicates log-rank test