Table I.
Sociodemographic and clinical data of patients with positive patch test reactions to PPDA and derivatives
| Parameter | Total | Female | Male | P-value |
|---|---|---|---|---|
| Total number of patients (%) | 4087 (100) | 2730 (66.8) | 1357 (33.2) | < 0.001 |
| Number of positive results (%) | 166 (4.06) | 120 (4.4) | 46 (3.4) | 0.126 |
| Sex, n (%) | 166 (100) | 120 (72.3) | 46 (27.7) | < 0.0001 |
| Age [years]: | ||||
| Mean | 43.27 ±16.4 | 41.54 ±15.8 | 46.22 ±18.7 | 0.1070 |
| Range | 12–88 | 12–88 | 15–77 | |
| Social background, rural/urban, n (%) | 45/121 (27.1/72.9) | 27/93 (22.5/77.5) | 18/28 (39.1/60.9) | 0.031# |
| Association with occupational work (%): | ||||
| Proven | 57 (34.3) | 30 (25) | 27 (58.7) | < 0.0001# |
| Possible | 18 (10.8) | 11 (9.2) | 7 (15.2) | 0.26 |
| Not associated | 91 (54.8) | 79 (65.8) | 12 (26.1) | < 0.0001# |
| Disease duration [years]: | ||||
| Mean | 4.12 ±5.4 | 4.23 ±5.87 | 3.83 ±4.23 | 0.7266 |
| Range | 0.1–35 | 0.1–35 | 0.2–22 | |
| Atopy, in family/in patient, n (%) | 50/61 (30.1/36.7) |
39/50 (32.5/41.7) |
11/11 (23.9/23.9) |
0.27/0.03# |
| Clinical characteristics, n (%): | ||||
| Hand dermatitis | 56 (33.1) | 42 (35) | 14 (30.4) | 0.5747 |
| Disseminated eczema | 47 (28.3) | 31 (25.8) | 16 (34.8%) | 0.249 |
| Facial dermatitis | 27 (16.3) | 26 (21.7) | 1 (2.2) | 0.0023# |
| Hands and feet dermatitis | 16 (9.6) | 8 (6.7) | 8 (17.4) | 0.0368# |
| Feet dermatitis | 4 (2.4) | 2 (1.7) | 2 (4.3) | 0.329 |
| Leg eczema | 7 (4.2) | 3 (2.5) | 4 (8.7) | 0.07 |
| Eczema of other body areas | 5 (3.0) | 5 (4.2) | 0 | 0.158 |
| Urticaria | 2 (1.2) | 2 (1.7) | 0 | 0.373 |
| Erythema multiforme-like lesions | 1 (0.6) | 0 | 1 (2.2) | 0.485 |
#
Statistically significant, p < 0.05.