Table II.
Positive patch test reactions to the respective aromatic amines, other chemicals cross-reacting to PPDA and the reaction grade
| Allergen | Number (%)* of positive results | Reaction grade, n total (%)** (F/M) | |||||
|---|---|---|---|---|---|---|---|
| Total N = 166 | Female n = 120 | Male n = 46 | P-value | + | ++ | +++ | |
| PPDA | 128 (77.1) | 94 (78.3) | 34 (73.9) | 0.54 | 53 (41.4) (35/18) |
42 (33.0) (32/10) |
33 (25.8) (27/5) |
| IPPD | 34 (20.5) | 17 (14.2) | 17 (36.9) | 0.032 | 21 (61.7) (16/5) |
4 (11.8) (1/3) |
9 (26.5) (0/9) |
| TDA | 10 (6.0) | 10 (8.3) | 0 | 0.0002 | 5 (50) (5/0) |
5 (50) (5/0) |
0 |
| TETA | 2 (1.2) | 0 | 2 (4.3) | 0.315 | 2 (100) (0/2) |
0 | 0 |
| EDA | 1 (0.6) | 0 | 1 (2.15) | 0.487 | 0 | 0 | 1 (0/1) |
| Paraben mix | 8 (4.8) | 3 (2.5) | 5 (10.9) | 0.024 | 6 (75) (2/4) |
2 (100) (1/1) |
0 |
| Benzocaine/Caine mix | 18 (10.8) | 13 (10.8) | 5 (10.9) | 0.99 | 7 (38.9) (6/1) |
5 (27.8) (4/1) |
6 (33.3) (3/3) |
*
Percentage calculated in relation to the total number of patients with positive patch tests (total, F, M)
**
percentage calculated in relation to the total number of patients with positive patch test reactions to a respective allergen.
PPDA – paraphenylenediamine, IPPD – N-isopropyl-N-phenyl-4-phenylenediamine, TDA – toluene-2,5-diamine, TETA – triethylenetetramine, EDA – ethylenediamine.