Table 3.
Demographics, disease characteristics, and patient-reported measures of patients with normal vs. abnormal salivary gland ultrasound studies
| Normal US N = 20 (%)a | Abnormal US N = 11 (%)a | p-value | |
|---|---|---|---|
| Demographics | |||
| Age, years, Mean (SD) | 18.0 (2.5) | 19.6 (2.6) | 0.11 |
| Female | 18 (90) | 9 (82) | 1.00 |
| Caucasian | 13 (65) | 4 (36) | 0.15 |
| Black/African American | 6 (30) | 7 (64) | 0.13 |
| Disease characteristics | |||
| Disease Duration, years, Mean (SD) | 4.5 (3.5) | 5.9 (3.6) | 0.31 |
| SLEDAIb, Median (IQR) | 2.0 (0.0–4.0) | 4.0 (1.0–5.0) | 0.74 |
| Anti-dsDNAc | 15 (75) | 6 (55) | 0.24 |
| Anti-Smithc | 10 (50) | 6 (55) | 1.00 |
| Anti-RNPc | 13 (65) | 9 (82) | 0.43 |
| Anti-Roc | 6 (30) | 9 (82) | 0.01 |
| Anti-Lac | 1 (5) | 4 (36) | 0.04 |
| IgGd mg/dL, Mean (SD) | 1323.4 (559.6) | 2017.3 (825.7) | 0.01 |
| Patient-reported measures | |||
| Dryness Scoree, Median (IQR) | 0.5 (0.0–3.0) | 3.0 (1.5–5.0) | 0.09 |
| Fatigue Scoree, Median (IQR) | 2.5 (0.8–4.0) | 2.0 (1.0–5.5) | 0.80 |
| Pain Scoree, Median (IQR) | 1.0 (0.0–3.0) | 1.0 (0.0–4.0) | 0.86 |
| Needs water to swallow | 4 (20) | 3 (27) | 0.68 |
| Episodic cheek swelling | 3 (15) | 1 (9) | 1.00 |
a Number of patients with percentage unless noted; b SLEDAI: Systemic Lupus Erythematosus Disease Activity Index, most recent value; cAny history of antibody positivity; d IgG level at disease diagnosis; eDryness, Fatigue, and Pain scores on a scale of 0–10 with 10 being the worst score