Physiochemical properties and descriptors for front-line and impactful TB drugs. Background colouration reflects positioning of drug with respect to i) Lipinski parameters (MW, molecular weight, in Daltons <500; clog P, calculated log partition coefficient <5; HBD hydrogen bond donors <5 and HBA acceptors <10); ii) GSK log D_7.4–CMR positioning (see Fig. 4) and iii) property forecast index values PFI <6.