Fig. 6.

Taking Fig. 5A and C which now represents Fig. 6A and 6B respectively. Comparison of the external dose-response formation of three metabolites formed, (1) hydroxylation (AMLHME), (2) sulfation (AMLSME), (3) glucuronidation (AMLGME), using the estragole model in a read across manner versus the original methyleugenol (ME). Part A = estragole model but changing the MW and PC values of methyleugenol and its metabolites; Part B changing also the kinetic constant of methyleugenol metabolite based on the proposed biotransformation pathways of estragole.