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. 2021 May 18;16(5):e0250820. doi: 10.1371/journal.pone.0250820

Fig 2. Long-term follow-up of patient started on teriflunomide between 2013 and 2019.

Fig 2

Percentage of relapse-free patients in the whole cohort (A) during the follow-up, stratified by sex (B) and history of previous treatment (C). Percentage of patients free of 6-months confirmed disability worsening (CWD) in the whole cohort (D) during the follow-up, stratified by sex (E) and history of previous treatment (F). There were no male patients registered with relapse or CDW after 4.5 years, therefore the curves are shorter for males than females in B and E. Cumulative incidence of discontinuation due to adverse events in the whole cohort (G), stratified by sex (H) and history of previous treatment (I). Cumulative incidence of discontinuation due to disease breakthrough in the whole cohort (J), stratified by sex (K) and history of previous treatment (L).