Comparison 4. Carbacephem versus penicillin.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
4.1 Resolution of symptoms post‐treatment (ITT analysis)	3	795	Odds Ratio (M‐H, Random, 95% CI)	0.70 [0.49, 0.99]
4.1.1 Adults	2	562	Odds Ratio (M‐H, Random, 95% CI)	0.75 [0.46, 1.22]
4.1.2 Children	1	233	Odds Ratio (M‐H, Random, 95% CI)	0.57 [0.33, 0.99]
4.2 Resolution of symptoms post‐treatment (evaluable participants)	3	602	Odds Ratio (M‐H, Fixed, 95% CI)	0.62 [0.38, 1.01]
4.2.1 Adults	2	410	Odds Ratio (M‐H, Fixed, 95% CI)	0.59 [0.31, 1.13]
4.2.2 Children	1	192	Odds Ratio (M‐H, Fixed, 95% CI)	0.66 [0.32, 1.38]
4.3 Incidence of relapse (evaluable participants)	3	523	Odds Ratio (M‐H, Fixed, 95% CI)	1.27 [0.64, 2.50]
4.4 Adverse events (ITT analysis)	3	795	Odds Ratio (M‐H, Random, 95% CI)	1.08 [0.75, 1.55]