Skip to main content
. 2020 Nov 25;2020(11):CD001159. doi: 10.1002/14651858.CD001159.pub3
Review Pain  Acute confusional state Myocardial infarction Chest infections Death Time to first mobilization Cost of analgesic regimen  Remarks
Amin 2017 FICB is safe and effective in controlling perioperative pain N/A N/A N/A N/A N/A N/A NR 
25 trials
 
Dizdarevic 2019 Utilize various strategies to reduce pain including RA N/A N/A N/A N/A N/A N/A NR
 
Fadhlillah 2019
  FICB reduces acute pain on movement
Variable results for pain at rest
N/A
  N/A
  N/A
  N/A
  N/A
  N/A
  MA
8 RCTs
Freeman 2016 FICB is part of recommended
practices Use multi‐modal analgesia to
reduce the incidence of delirium N/A N/A N/A N/A N/A NR
 
Hards 2018 FICB is suitable for  pre‐hospital use and has few adverse effects
Comparisons with systemic opioids are required
N/A N/A N/A N/A N/A N/A SR
7 studies:
  • 1 RCT

  • 4 P

  • 1 R

  • 1 CR

Hartmann 2017 FNB seemed to be more effective than IV fentanyl  N/A N/A N/A N/A N/A N/A SR
2 RCTs
 
Hong 2019 FICB reduced pain at 1 to 8, 12, 24, and 48 hours
No difference at 72 hours
N/A N/A N/A N/A N/A N/A MA
11 RCTs
 
Hsu 2018
  Limited evidence for
reduced pain on movement at 30 minutes and at 6 hours after surgery  with FICB
No significant complications
 
N/A N/A N/A N/A N/A N/A MA
3 RCTs
Hsu 2019
  FNB achieved lower pain scores on movement at 30 minutes than IV analgesia N/A N/A N/A N/A N/A N/A MA
10 studies
  • 8 RCTs 

  • 2 P 

Parker 2016
  N/A N/A N/A N/A Nerve blocks may reduce mortality or morbidity
Continuing research
is required 
N/A N/A NR
 
Rashiq 2013
  ONB plus LFCNB had the highest probability of being effective against acute postoperative pain
More trials comparing multiple nerve blocks in hip fractures are required
FICB had the highest probability of being the most effective N/A N/A N/A N/A N/A SR
21 RCTs
Scurrah 2018
  Consistent evidence that PNBs reduce pain and are more effective than standard systemic analgesia alone
  Moderate evidence for a reduction
  N/A N/A Limited evidence for a reduction 
  N/A N/A NR
Skjold 2019
  Limited quantity of evidence for decreased pain scores leading to  very low certainty of evidence supporting preoperative single‐injection
FNBs
  N/A N/A N/A N/A N/A N/A SR with MA
5 RCTs
 
Soffin 2019
  PNBs and non‐opioid multi‐modal analgesic agents are suggested preoperatively 
  N/A N/A N/A N/A N/A N/A ER
 
Steenberg 2018
FICB superior to opioids during movement
Very few adverse effects
 
Insufficient evidence
  N/A N/A Insufficient evidence N/A N/A SR
11 studies
  • 8 RCTS

  • 3 qRCTs

CR: Case report; ER: evidence review; FICB: fascia iliaca compartment block; FNB: femoral nerve block;
LFCNB: lateral femoral cutaneous nerve block; IV: intravenous; N/A: not a purpose of the review;  
MA: meta‐analysis; NR: narrative review; ONB: obturator nerve block; P: prospective non‐randomized trial;
PNB: peripheral nerve block: qRCT: quasi‐randomized controlled trial; RA: regional anaesthesia;
RCT: randomized controlled trial;  R: retrospective trial; SR: systematic review.