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. 2020 Nov 25;2020(11):CD001159. doi: 10.1002/14651858.CD001159.pub3

Cuvillon 2007.

Study characteristics
Methods Parallel RCT
Approved by the ethics committee and written informed consents obtained
Site: Centre Hospitalier Universitaire de Nîmes, France
Data collection: September 1999 to June 2002
Funding: charity
Registration: no information
Participants 62 ASA physical status I to IV, ≥ 70 years of age, with proximal end femur fracture undergoing surgery
Excluded: more than 72 hours between fracture and surgery, weight < 40 kg, ASA physical status > IV, neurological disease (alcoholic or diabetic), allergy or contraindication to regional anaesthesia, severe hepatic or renal dysfunction, Mini Mental score < 15/30
Type of fracture: proximal end femur fracture
Anaesthetic technique for surgery: spinal block
Surgical technique: plate and screw (58%) or intermediate prosthesis (42%)
Mean age: 82 years (range not stated)
Percentage female: 86%.
Length of follow‐up: in‐hospital
Interventions Intervention: continuous femoral nerve block (N = 21)
Comparator: no nerve block (N = 41)
Outcomes Relevant to this review.
  1. Pain.

  2. Acute confusional state.

  3. Mortality.

  4. Pneumonia.

  5. Time to first mobilization after surgery.

  6. Cost of analgesic regimens.

  7. Opioid requirement.

  8. Pressure sores.


Not relevant to this review.
  1. Transfused.

Notes Conflict of interest: not mentioned
DOI: 10.1016/j.annfar.2006.06.025
Study authors contacted 22 May 2015; no reply
Sources obtained for risk of bias assessment.
  1. Journal article with results of the trial.