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. 2020 Nov 25;2020(11):CD001159. doi: 10.1002/14651858.CD001159.pub3

Morrison 2008.

Study characteristics
Methods Parallel RCT
Approved by the ethics committee and informed consents obtained
Site: 3 university hospitals: Beth Israel, Icahn School of Medicine at Mount Sinai, and Maimonides Medical Center, New York, NY, USA
Data collection: April 2009 to March 2013
Funding: governmental
Registration: NCT00749489
Participants 164 adult patients 60 years of age and over, presenting from 08H00 to 20H00 with a radiographically confirmed hip fracture (femoral neck, intertrochanteric, or pericapsular)
Excluded: history of advanced dementia, presence of multiple trauma, pathological fractures, bilateral hip fractures, previous fracture or surgery at the currently fractured site, transferred from another hospital, with cirrhosis or liver failure, had a delay between fracture and admission > 48 hours, were delirious according to the Confusion Assessment
Type of fracture: femoral neck (40.5%) or femoral intertrochanteric fracture
Anaesthetic technique for surgery: regional (62.1%) or general anaesthesia
Surgical technique: hemi‐arthroplasty (29%) or internal fixation
Mean age: 82.5 years (range 60 to 98)
Percentage female: 72.6%
Length of follow‐up: 6 weeks
Interventions Intervention: femoral nerve block followed by a continuous fascia iliaca block (N = 72)
Comparator: no nerve block (N = 81)
Outcomes Relevant to this review.
  1. Pain.

  2. Mortality.

  3. Acute confusional state.

  4. Opioid consumption.

  5. Complications.


Not relevant to this review.
  1. Distance walked on postoperative day 3.

  2. Walking ability 6 weeks after discharge.

  3. Opioid side effects.

  4. Hospital length of stay.

  5. In‐hospital falls.

Notes Conflict of interest: "the editor‐in‐chief has reviewed the conflict of interest checklist provided by the authors and has determined that the authors have no financial or any other kind of personal conflicts with this paper. Dr. Silverstein died before the study’s completion. At the time of his death, he reported no conflicts of interest"
DOI: 10.1111/jgs.14386
Email sent on 5 January 2020
Sources obtained for risk of bias assessment.
  1. Journal articles with results of the trial.

  2. Non‐commercial trial registry record.

  3. Conference abstracts about the trial.