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. 2020 Nov 25;2020(11):CD001159. doi: 10.1002/14651858.CD001159.pub3

Uysal 2018.

Study characteristics
Methods Parallel RCT
Approved by the ethics committee and informed consent obtained
Site: Mugla Sitki Koçman University Training and Research Hospital,  Isparta, Turkey
Data collection: 15 April 2018 to 18 May 2018
Funding: departmental/institutional
Registration: ACTRN12618000546257
Participants 110 ASA II to IV participants > 65 years of age with hip fracture
Excluded: preexisting delirium at admission to emergency service, femur fracture due to metastatic carcinoma, bupivacaine allergy, cholinesterase inhibitor or levodopa medication, parkinsonism or epilepsy, contraindication for nerve blockage. Patients operated longer than 48 hours after admission were excluded from the trial
Type of fracture: trochanteric femur fracture
Anaesthetic technique for surgery: combined spinal/epidural; both groups had postoperative epidural analgesia
Surgical technique: no information
Mean age: 81.7 years (range not stated)
Percentage female: 44%
Length of follow‐up: 3 days
Interventions Intervention: continuous femoral nerve block (N = 46)
Comparator: no nerve block and IV paracetamol (N = 45)
Outcomes Relevant to this review.
  1. Pain (postoperative pain scores not retained because both groups had postoperative epidural analgesia).

  2. Acute confusional state. 

  3. Mortality (not retained for this review because all participants received epidural analgesia after surgery).


Not relevant to this review.
  1. Inflammation (including CSF measurements sampled during spinal blockade).

  2. Rescue analgesia.

Notes Conflict of interest: "none declared"
DOI: 10.14744/tjtes.2019.78002
Email sent to authors 23 January 2020
Sources obtained for risk of bias assessment.
  1. Journal article with results of the trial.

  2.  Non‐commercial trial registry record.