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. 2020 Nov 25;2020(11):CD001159. doi: 10.1002/14651858.CD001159.pub3

Cong 2016.

Study name Nerve block anesthesia and general anesthesia: influence on postoperative cognitive dysfunction after hip arthroplasty of aged patients with femoral neck fracture (a randomized controlled trial)
Methods Parallel RCT
Approved by the ethics committee and informed consents obtained
Site: Shanghai 10th Hospital, Shanghai, China
Data collection: 1 June 2017 to 1 October 2019
Funding: departmental/institutional
Registration: ChiCTR‐INR‐16009481
Participants 100 participants between 60 and 80 years of age with normal mental status and unilateral hip fracture undergoing hip arthroplasty
Excluded: severe respiratory disease, preoperative cognitive dysfunction
Type of fracture:  femoral neck fracture
Anaesthetic technique for surgery:  to be determined
Surgical technique: hip arthroplasty
Mean age: (range ): to be determined
Percentage female: % to be determined
Length of follow‐up:  3 months
Interventions Intervention 1: nerve block plus enhanced recovery protocol (N = 25)
Intervention 2: nerve block without enhanced recovery protocol (N = 25)
Comparator 1: no block plus general anaesthesia (N = 25)
Comparator 2: no block and no general anaesthesia (N = 25)
Outcomes Relevant to this review.
  1. Acute confusional state (up to 3 months after surgery).


Not relevant to this review.
  1. Cognition function.

  2. Bispectral index.

  3. S100B protein.

  4. Functional recovery.

  5. Cerebral oxygen saturation.

  6. Minerals.

Starting date First posted: 18 October 2016
Study start date: to be determined
Study completion date: to be determined
Last update posted: 18 April 2017
Contact information Ruijun Cong
Notes Conflict of interest: to be determined
DOI: to be determined