Li 2018.

Study name	Effect of continuous lumbar plexus block combined with dexmedetomidine on postoperative delirium in elderly patients with hip fractures: a prospective, randomized controlled trial
Methods	Parallel RCT Approved by the ethics committee and informed consent obtained Site: Shanghai General Hospital, China Data collection: to be determined Funding: departmental/institutional Registration: ChiCTR1900021549
Participants	280 ASA I to III participants ≥ 65 years of age with hip fracture undergoing surgery Excluded: compound injury (multiple fractures, combined with trauma of the head, chest, abdomen, pelvis, and parts other than the hip), contraindications for lumbar plexus block (puncture site infection, peripheral neuropathy, local anaesthetic allergy, etc.), coexisting neurological disease (Alzheimer's disease, vascular dementia, and other diseases that affect cognitive function), allergy to the test drug, participated in other clinical trials Type of fracture: hip fracture Anaesthetic technique for surgery: to be determined Surgical technique: to be determined Mean age (range ): to be determined Percentage female: % to be determined Length of follow‐up: 7 days
Interventions	Intervention 1: continuous posterior lumbar plexus block and dexmedetomidine (N = 70) Intervention 2: continuous posterior lumbar plexus block and no dexmedetomidine (N = 70) Comparator 1: no block and dexmedetomidine (N = 70) Comparator 2: no block and no dexmedetomidine(N = 70)
Outcomes	Relevant to this review. Pain. Mortality. Opioids. Complications. Not relevant to this review. Cognitive function. Inflammation. Quality of life.
Starting date	First posted: 27 February 2019 Study start date: 15 March 2019 Study completion date: 15 March 2021 Last update posted: 27 February 2019
Contact information	Jin Bao LI, Jian Hai Zhang
Notes	Conflict of interest: to be determined DOI: to be determined