Study |
Bias |
Randomisation process |
Deviations from intended interventions |
Missing outcome data |
Measurement of the outcome |
Selection of the reported results |
Overall |
Authors' judgement |
Support for judgement |
Authors' judgement |
Support for judgement |
Authors' judgement |
Support for judgement |
Authors' judgement |
Support for judgement |
Authors' judgement |
Support for judgement |
Authors' judgement |
Support for judgement |
Fletcher 2003 |
Low risk of bias |
The randomization sequence was derived from a random number generator, and allocation concealment was achieved by means of the sealed opaque envelope method. No baseline differences between intervention groups identified. |
Low risk of bias |
No deviations from intended interventions identified. |
Low risk of bias |
100% of included participants were analyzed. |
Low risk of bias |
Lower respiratory tract infections determined by a blinded assessor. |
Low risk of bias |
No deviation to the planned statistical analysis identified. Only one result provided. |
Low risk of bias |
No risk of bias identified. |
Haddad 1995 |
Low risk of bias |
Randomized by sealed envelope. No baseline differences between intervention groups identified. |
Low risk of bias |
No deviations from intended interventions identified. |
Low risk of bias |
90% of included participants were analyzed. |
Low risk of bias |
Chest infections which required antibiotics. We judged it as unlikely to have been influenced by knowledge of the treatment group. |
Low risk of bias |
No deviation to the planned statistical analysis identified. Only one result provided. |
Low risk of bias |
No risk of bias identified. |
White 1980 |
Low risk of bias |
Patients were randomly allocated. No baseline differences between intervention groups identified. |
Low risk of bias |
No deviations from intended interventions identified. |
Low risk of bias |
80% of included participants were analyzed. |
Low risk of bias |
Pneumonia. We judged it as unlikely to have been influenced by knowledge of the treatment group. |
Low risk of bias |
No deviation to the planned statistical analysis identified. Only one result provided. |
Low risk of bias |
No risk of bias identified. |