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. 2021 May 14;13:3953–3961. doi: 10.2147/CMAR.S310773

Table 1.

Demographics and Pathological Characteristics of Patients with PTC Stratified by Hashimoto’s Thyroiditis

Variables PTC with HT PTC without HT P
SEX (F/M) 548/50 1731/597 <0.001
Age 43 (34~53) 45 (36~53) 0.049
TSH 2.01 (1.316~2.964) 1.716 (1.146~2.458) <0.001
TPOAb 16.57 (1~246.26) 1 (1~1.8) <0.001
TgAb 35.765 (7.642~184.852) 1.03 (0.4~2.347) <0.001
Tumor size 0.8 (0.6~1.2) 0.8 (0.6~1.3) 0.708
Focality (Multifocal/unifocal lesions) 210/388 769/1559 0.335
Unilaterality/bilateral lesions 469/129 1790/538 0.424
PTC Classical subtype (Yes/No) 565/33 2243/85 0.038
p T stage (I+II/III+IV) 339/259 1174/1154 0.006
ETE (Yes/No) 258/340 1151/1177 0.006
LV invasion (Yes/No) 2/596 40/2288 0.011
Intrathyroidal spreading (Yes/No) 45/553 131/2197 0.082
LNM (N0/N1a/N1b) 330/179/89 1152/854/322 0.008
Central LNM (Yes/No) 179/330 854/1152 0.002
The average number of positive central LNs 0 (0~2) 0 (0~2.05) 0.037
The number of central LNS 7 (4~10) 4 (2~6) <0.001
Lateral LNM (Yes/No) 89/509 322/2006 0.333
The average number of positive lateral LNs 3 (1~5.5) 3 (1~6) 0.192
The average number of lateral LNs 19 (13~29) 19 (12~27) 0.817

Note: Variables in bold show statistical significance.

Abbreviations: ETE, extrathyroidal extension; LV invasion, lymphatic vascular invasion; LNM, lymph nodes metastasis; LNs, lymph nodes; PTC, papillary thyroid cancer; HT, Hashimoto’s thyroiditis.