Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model of the coagulopathies in coronavirus disease 2019 (COVID‐19) and sepsis. In patients with COVID‐19, increased tissue factor (TF) leads to fibrin generation but low D‐dimer due to the concurrent increase in plasminogen activator inhibitor 1 (PAI‐1) and inhibition of fibrinolysis. In sepsis, increased TF leads to fibrin generation with high D‐dimer due to a smaller increase in PAI‐1
