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. Author manuscript; available in PMC: 2022 May 17.
Published in final edited form as: Chem Res Toxicol. 2021 Jan 20:10.1021/acs.chemrestox.0c00386. doi: 10.1021/acs.chemrestox.0c00386

Figure 1. BACs reduce neurosphere growth.

Figure 1.

(A) Size distribution of neurospheres exposed to vehicle control, AY9944 (positive control), BAC C12, or BAC C16 at a concentration of 1, 10, 50, and 100 nM from DIV 4 to DIV 7. (B) Representative brightfield images of neurospheres exposed to a concentration of 50 nM from DIV 4 to DIV 7 (scale bar: 400 μm). (C) Number of neural progenitor cells from dissociated neurospheres exposed to vehicle control (0 nM), AY9944, BAC C12, or BAC C16 at 10 and 50 nM from DIV 4 to DIV 7. N = 4 biological replicates per condition. Adjusted P value: *, P < 0.05; **, P < 0.01; ***, P < 0.001.