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. Author manuscript; available in PMC: 2022 May 17.
Published in final edited form as: Chem Res Toxicol. 2021 Jan 20:10.1021/acs.chemrestox.0c00386. doi: 10.1021/acs.chemrestox.0c00386

Figure 4. BACs induce apoptosis of NPCs.

Figure 4.

(A) Immunocytochemistry for TUNEL (green) counterstained with DAPI (blue) of NPCs exposed to vehicle control (0 nM) or 50 nM of BAC C12 or BAC C16 from DIV 4 to DIV 7. (B) Quantification of percentage of TUNEL-positive NPCs. (C) DAPI-stained nuclei for each exposure group. Enlarged image in bottom right corner shows condensed nuclei. (D) Quantification of percentage of condensed nuclei. N = 4 biological replicates per condition. Adjusted P value: *, P < 0.05; **, P < 0.01; ***, P < 0.001.