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N-glycan maturation pathway. N-glycans attached to proteins are trimmed by α-glycosidase (Gls), type I α-1,2-mannosidase (Man I) and type II α-mannosidase (Man II) enzymes. The latter steps can be inhibited by kifunensine (1) and swainsonine (2) respectively. Elaboration of the N-glycans is facilitated by N-acetyl glucosamine transferase I (GnT I), galactosyl transferase (GalT) and sialyl transferase (ST) enzymes.
