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. 2021 Feb 6;24(2):348–369. doi: 10.1007/s10567-020-00335-z

Table 3.

Differences between conditions and associations between characteristics of exposure and anxiety outcomes, by assessment timepoint

Construct Study Anxiety Type Studies (n) Effect Size by assessment timepoint Cohen’s d or r
Before exposure
DCS 1 h before exposure Farrell et al. (2013) OCD (difficult to treat) 1

PT = 0.00

1 m = -0.50

3 m = -0.40

NE

Medium

Small

d

Pa: PT =  − 0.15

Pa: 1 m =  − 0.69

Pa: 3 m = 0.22

NE

Large

Small

d
Storch et al (2010) OCD 2 PT = -0.67 Medium d
Storch et al (2016) PT = ⋄ - -
Leyfer et al (2019) Panic 1

PT = 0.18

3 m = 0.04

NE

NE

d
Scheeringa and Weems (2014) PTSD 1

PT = 0.71

3 m = 0.62

Medium

Medium

d
Byrne et al. (2015)
Same context Specific Phobia 1 1w = 0.19 Small r
Novel context 1w = -0.37* Medium r
DCS at the commencement of exposure Farrell et al (2018) Specific Phobia 1

PT = ⋄

1 m = ⋄

3 m = ⋄

-

-

-

-

-

-

Rapee et al (2016) Mixed 1 PT = 0.56 Medium d
Pa: PT = -0.23 Small
Sertraline

Storch et al (2013)

RegSert

OCD 2 PT = −0.02 NE d
SlowSert PT = 0.23 Small d
The POTS Study (2004) PT = −0.31** Small d
Attention Training to Positive Stimuli (ATP) Waters et al (2014) Specific phobia 1

PT = 0.25

3 m = 0.12

Small

NE

d
Observational Learning

Menzies and Clarke (1993)

Same context

Fear of Water 2

PT = ⋄

12w = ⋄*

- -
Novel Context 1w = ⋄ -

Weiss et al (1998)

Peer Mastery

PT = -0.60*

4d = -0.42

Medium

Small

d
Peer Coping

PT = -0.50*

4d = -0.11

Medium

NE

d
Social Skills Training Olivares-Olivares et al (2019) Social 1

PT = 1.06Δ***

6 m = 1.00Δ***

12 m = 0.95Δ***

Large

Large

Large

d
Preparation Tiwari et al (2013) Mixed 1 PT = 0.15Δ♦ Small r
Within exposure
Quantity of Exposure Hedtke et al (2009) Mixed 1 PT = ⋄*
Benito et al (2018) OCD 2 PT = ⋄
Kircanski & Peris (2015)

PT = ⋄

3 m = ⋄

Time spent on Exposure

Hedtke et al (2009)

Average length of exposure tasks per session

Mixed 1 PT = ⋄

Benito et al (2018)

Duration of exposures

OCD 2 PT = ⋄

Kircanski & Peris (2015)

Minutes spent on ERP tasks per session

OCD

PT = ⋄

3 m = ⋄

Cumulative Dose of Exposure Peris et al (2017) Mixed 1 PT = ⋄*** - -
Percentage of Session with Exposure Peris et al (2017) Mixed 1 PT = ⋄*** - -
Percentage of Session with Difficult Exposure Peris et al (2017) Mixed 1 PT = ⋄*** - -
Proportion of Session with Combined Exposure Kircanski & Peris (2015) OCD 1

PT = ⋄

3 m = ⋄

-

-

-
Frequency of Exposure Task Type Hedtke et al (2009) Mixed 1 PT = ⋄ - -
Location of Exposure Task Hedtke et al (2009) Mixed 1 PT = ⋄ - -
Safety Seeking Hedtke et al (2009) Mixed 1 PT = -0.37Δ♦* Medium r
Cognitive Strategy Benito et al (2012) OCD 1 PT = ⋄ - -
Avoidance Statement 1 PT = ⋄ - -
Avoidant Behaviour 1 PT = ⋄ - -
Compliance Peris et al (2017) Mixed 1 PT = ⋄*** - -
Mastery Peris et al (2017) Mixed 1 PT = ⋄*** - -
Coping Hedtke et al (2009) Mixed 1 PT = 0.11Δ♦ Small r
Processing Hayes et al (2017) PTSD 2
Negative Emotion PT = 0.21♦ Small r
Avoidance PT = 0.00♦ NE r
Ruminative Processing PT = 0.06♦ NE r
Decentring PT = -0.02♦ NE r
Ready et al (2015)
Overgeneralisation (beliefs)

PT = 0.15

6 m = 0.24*

9 m = -0.12

1y = 0.08

Small

Small

Small

NE

r
Accommodation

PT = -0.12

6 m = -0.16

9 m = 0.09

1y = 0.19

Small

Small

NE

Small

r
Initial distress Kircanski & Peris (2015) OCD 1

PT = ⋄

3 m = ⋄

-

-

-
Fear activation Hedtke et al (2009) Mixed 2 PT = ⋄ - -
Peterman et al (2016)

PT = -0.11

1y = -0.16

Small

Small

r
Benito et al (2018) OCD 1 PT = ⋄ - -
Fear Reduction Peterman et al (2016) Mixed 2
Between session

PT = 0.00

1y = -0.05

NE

NE

r
Within session

PT = -0.20

1y = -0.17

Small

Small

r
Waters et al (2015) PT = 0.42Δ* Medium r
Benito et al (2018) OCD 2 PT = ⋄* -
Kircanski & Peris (2015)

PT = ⋄

3 m = ⋄

50% Rule Peterman et al (2016) Mixed 1

PT = -0.08

1y = -0.05

NE

NE

r
Variability of distress Waters et al (2015) Mixed 1 PT = 0.50Δ** Large r
Benito et al (2018) OCD 2 PT = ⋄ - -
Kircanski and Peris (2015)

PT = ⋄

3 m = -0.40Δ♦*

-

Medium

-

r

Expected minus actual distress Kircanski & Peris (2015) OCD 1

PT = ⋄

3 m = ⋄

-

-

-
Final distress Kircanski & Peris (2015) OCD 1

PT = ⋄

3 m = ⋄

-

-

-
Parent involvement Hedtke et al (2009) Mixed 1 PT = ⋄ - -

Benito et al (2012)

Discourage avoidance

OCD 1

PT = ⋄

3 m = 0.84Δ**

-

Very Large

-

r

Externalising statements

PT = ⋄

3 m = ⋄

-

-

-
Ollendick et al (2015) Specific Phobia 2

PT = 0.24

1 m = 0.17

6 m = 0.20

Small

NE

Small

d
Ost et al. (2001)

PT = 0.25

1y = 0.17

BAT PT = ⋄

BAT 1y = ⋄

Small

NE

-

-

d

-

Therapist Involvement

Benito et al (2012)

Discourage avoidance

OCD 1

PT = ⋄

3 m = 0.73Δ**

-

Very Large

r
Unrelated Talk

PT = ⋄

3 m = ⋄

-

-
Exposure comments (to increase anxiety)

PT = ⋄

3 m = ⋄

-

-

-
After exposure
Child processing Tiwari et al (2013) Mixed 1 PT = 0.18Δ♦* Small r
DCS after exposure Mataix-Cols et al. (2014) OCD 1

PT = 0.07

3 m = 0.10

6 m = 0.19

1y = 0.15

NE

NE

NE

NE

d
Between sessions
Fear Reduction Peterman et al (2016) Mixed 1

PT = 0.00

1y = −0.05

NE

NE

r
Kircanski & Peris (2015) OCD 2

PT = ⋄

3 m = ⋄

Kircanski, Wu and Piacentini (2014) PT = ⋄**
PaPT = ⋄***
Homework Compliance Park et al (2014) OCD 1 PT = -0.65 Large r

Pa = parent report; PT = post-treatment; Follow-up: d = day, w = week, m = month, y = year; For between-subject studies (d): negative effect indicates lower anxiety level for “EXP plus” condition; positive effect indicates lower anxiety level for “EXP only/placebo” control condition; Δ = measure reported as change between assessment timepoints so that a higher score indicates a greater reduction in anxiety; ♦ = r imputed from β coefficients using Peterson and Brown’s (2005) imputation approach; □ = effect size calculated using available data; ⋄ = insufficient data available to calculate effect size; *p < .05, ** p < .01, *** p < .001; NE = did not meet the threshold for a small effect, BAT Behavioural Approach Test