Yang et al. (2020)8
|
AHNAK2, CDH3, IFI27, ITGA2, LAMB3, SFN, SLC6A14, and TMPRSS4 |
Pancreatic secretion, pathways in cancer, p53 signaling pathway, MAPK signaling pathway, Insulin signaling pathway, and pancreatic cancer |
AHNAK2, CDH3, IFI27, ITGA2, LAMB3, SLC6A14, and TMPRSS4 may have great diagnostic and prognostic value for pancreatic cancer |
Jin et al. (2020)7
|
TOP2A, CDK1, PRM2, PRC1, NEK2, ZWINNT1, DTL, MELK, CENPF, CEP55, ANLN, ASPM, and ECT2
|
ECM–receptor interaction, focal adhesion, pathways in cancer, proteoglycans in cancer, p53 signaling pathway, and PI3-Akt signaling pathway |
CDK1, TOP2A, and CEP55 may play pleiotropic roles in the progression of pancreatic cancer |
Li et al. (2019)26
|
ALB, COL1A2, EGF, COL3A1, FN1, CEL, ITGA2, COL5A2, MMP1, and CELA3B |
Protein digestion and absorption, ECM–receptor interaction, pancreatic secretion, and fat digestion and absorption |
COL1A2, COL3A1, and COL5A2 may promote pancreatic fibrosis and EMT via the ECM–receptor interaction pathway in the early stages of pancreatic cancer |
Liu et al. (2019)27
|
HN1, ITGA2, S100A6, KIF1A, DYM, and BACE1 |
Ubiquitin-mediated proteolysis and pathways in cancer |
HN1, ITGA2, and S100A6 may be promising potential targets for diagnosing and treating pancreatic cancer |
Shen et al. (2018)31
|
RPL13, RPL17, RPL21, RPL22, RPL23, RPL26, RPL31, RPL35A, RPL36A,RPL37, RPL39, RPL7, RPS17, RPS23, RPS3A,RPS6, RPS7, NUP107, NUP160, and HNRNPU
|
Ribosome pathway and the spliceosome pathway |
Nup170, Nup160, and HNRNPU may be used as possible molecular markers for early diagnosis of pancreatic cancer |
Pan et al. (2018)28
|
CXCL8, ADCY7, ITGAM, ITGB2, ITGB1, IL1A, ICAM1, ITGA2, THBS2, SDC1, COL3A1, COL1A2, COL1A1, MYL9, LAMA3, LAMB3, LAMC2, COL4A1 and FN1 |
ECM–receptor interaction, focal adhesion, pathways in cancer, and small cell lung cancer |
LAMA3, LAMB3, LAMC2, COL4A1, and FN1 may involve the malignant progression of pancreatic cancer |
Tang et al. (2018)6
|
DKK1 and HMGA2 |
Glycine, serine, and threonine metabolism |
DKK1 and HMGA2 may be important in the progression of pancreatic cancer |
Li et al. (2018)29
|
ALB, EGF, FN1, ITGA2, COL1A2, SPARC, COL3A1, TIMP1, COL5A1, COL11A1, and MMP7 |
ECM–receptor interaction, cell adhesion, and transforming growth factor-beta receptor signaling pathway |
ITGA2 and MMP7 may act as potential diagnostic and therapeutic biomarkers for pancreatic cancer |
Wang et al. (2015)30
|
VCAN, SULF1, COL8A1, FAP, COL1A1, THBS2, CTHRC1, COL1A2, COL6A3, FN1, COL10A1, COL3A1, TIMP, AEBP1, and COL5A1 |
ECM–receptor interaction, focal adhesion, and complement and coagulation cascades |
The collagen family genes and FN1 may play an essential role in the progression of pancreatic cancer |